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Conversely, the musical decoding can thus evidence of the spatial structure of a protein type. As we have just seen, the decoding of a protein at several levels can be controlled, including the decoding of molecules that are known to be metabolically agonist and the consistency of the predictions that are based on observed musical homologies for metabolism can be derived. Auf diese Weise kann man weite Teile des Stoffwechsels auf der molekularen Skala im Einzelnen rekonstruieren. In this way, one can reconstruct much of the metabolism at the molecular scale in detail.
For the subunit III of cytochrome oxidase, which linked musically with the cytochrome C, the beginning, in contrast, clearly a formula with four bars, such as the internal homologies illustrate simple so the notes share 7 to 22 put on by their contours remember the music of Bach, in groups of four with the following congruent notes.
At the eighth clock to find a time signature, which is not only congruent with all stressed bars of the first bar of cytochrome C, but in fact virtually identical to the third of the same cytochrome. Das bedeutet eine Dehnung des achten Taktes worauf die Kadenz am Ende dieses Taktes bereits selbst hinweist in einem Sechsertakt This means an expansion of the eighth clock after which the cadence at the end of this clock already himself points in a six-stroke 1 1 : :.
In In 1 1 wurde die Sequenz mit einer Anakruse begonnen, wodurch der betonte Takt wie weiter oben angegeben auf der dritten Note akzentuiert wird, zwecks Verkettung mit der rhythmischen Variante im CG-reichen Milieu des Cytochroms C. We give another example of the replica of the metabolic chain. Das Histon 4 ist eines der am besten erhaltenen Proteine des gesamten Tier- und Pflanzenreiches. The histone 4 is one of the best preserved proteins of the entire animal and plant kingdom. In fact, listeners have when they have heard the sound transposition of histone 4, repeated reports of "a desire to eat chocolate", containing magnesium some noticed even, "which is similar to magnesium in granular form, but that this effect here is immediately ".
What is like to note brings disadvantages for the people who have a little too high cholesterol. And actually contains the musical decoding of chalcone isomerase that behaves metabolically agonist for chalcone, but in stimulating musical "works better", a series of themes and variations, the succession in flowering plants the themes of the entire metabolic chain for regulation of cholesterol in humans reproduced: hearing this antagonist "second degree" of histone 4 allows so after in such situations generally applicable method , possibly to correct the detected secondary effect.
Moreover, the frequency of the four Ascendant, tends in chalcone isomerase to move closer to the frequency observed in the slightly alkaline myosin chain of mammals that stimulates muscle contraction while magnesium, as we know, acts as a muscle relaxer. The biochemical analysis of these epigenetic cooperations can where it is possible to be another valuable aid for the decoding.
Another well-known means of epigenetic stimulation of Muskeldekontraktion is heat, whose beneficial effects, for example, rheumatism well known. And actually, hsp27, which apparently most musical protein overlaid with the beginning of the hsp70, the richest, which plays the role of a bass here. These two molecules superimpose themselves with the beginning of troponin C, which regulates calcium in muscle contraction, and one would ascribe all the more important anti-rheumatic effect here as his musical level is high 4 4.
However, it must be stressed that in this type of suffering further molecules which also display a high musical level and are epigenetically sensitive may be involved, of the stimulation of prolactin and of the beta-Lipotropins precursor of beta-endorphin via inhibition of IgE and interleukin 1 Beta up to inhibition of the estrogen receptor.
These few examples show quite clearly how large. Parts of the metabolism can be reproduced faithfully, with a variety of approaches and methods to check the consistency of the results obtained or control and to clarify the musical decoding of the respective proteins. Applications IV.. For applications using transcription, either in the form of musical scores or recordings of musical sequences and spatial color representations of the proteins, together or separately, or else on any type of suitable support material disc, floppy disk, audio or video cassette, paper carrier, especially for color photographs.
The records of the musical sequences can be created on the basis of the scores described below 11 for we have given some examples in section III , after one of the BH in Repp, J. At the. However, the full integration of metabolically complex effects can take a long time to complete, or even in case of strong cultural conditioning some initial training required to make which apparently corresponds to the "re-education" of a hearing, which is transmitted by the originating from the microphonic of cochlear scalar , but which is generally due to the obvious interest of people affected is quite rapid.
For a responsible use of the method described, it is important to know the role of the molecules involved in the metabolism good. For an interest - that goes beyond the addressed here theurapeutischen frame without a doubt - the musical decoding of proteins and the corresponding colors is safe in carrying a flag as a musical and colored homologies and anti-homologies based on the known and databases available protein sequences to make the metabolically agonist and antagonist proteins locate a particular protein, the degree of musical expression, moreover, provides information on the scope of their metabolic role.
Thus, the described method allows specific information for specific protein sequences for which we earlier - in Section III - have given some examples should be specified.
In this context, it should be recalled that, in animal and vegetable proteins, especially in the most musical among them, often encounters consecutive melodic fragments of Stoffwechselkettten of man, and that the active transpositions to humans thus not to the human molecules limit, for which we have also cited examples in section III. Since the metabolism of these species on the contrary "specialized" appears in some way with regard to the production of certain molecules, it is the "most musical" proteins in general, which will be for the applications most important.
Of course, these similarities between different species facilitate the delimitation of the metabolic role and the actual decoding of the protein sequences. Finally, as regards the use of the transcripts of protein sequences, it can even allow for the speed of their effect by differential comparisons, particularly bipolar, distil their positive or negative effect, which is in a particular situation the most appropriate.
Verfahren zur epigenetischen Regulation, entweder durch Stimulation oder durch Inhibierung, der Biosynthese eines Proteins in situ durch Skalenresonanz, gekennzeichnet durch: A.
Process for epigenetic regulation of the biosynthesis of proteins by resonance of scale. Method for the epigenetic regulation of protein biosynthesis by scale resonance. EPB1 en. JPHA en. ATT en. AUB2 en. The importance of this kind of broader approach to the doubtlessly challenging topic of exile is impressively demonstrated in the volume edited by John Tolan. It is comprised of eleven essays in English and French that were presented at a conference held at Central European University, Budapest in June Accordingly, the articles present historical case studies of exile from different European and Mediterranean regions Hungary, England, the Iberian Peninsula, Egypt, and Malta , chronologically ranging from Antiquity to Early Modern times.
By combining these different examples, the editor has tried to shed light on the possible causes of expulsion, ways to integrate diasporic communities into their new societies, and meanings of memories of the country or culture of origin for the formation of group identities.
Hegel’s Aesthetics (Stanford Encyclopedia of Philosophy)
Tolan takes these case studies as a starting point to develop helpful general thoughts on the other two key aspects of the volume modes of integration and modes of constructing group identities of medieval diasporas. He thereby convincingly prepares the way for the following articles, several of which also examine case studies of Jewish diaspora experience. Three topographical figures and an appendix on the ways in which Jewish properties changed hands after the expulsion nicely complement the text.
In the next essay, another example from Egypt becomes the focus of interest. They do not focus on particular historical events but rather address certain source types, social ascriptions, or contemporary ways of dealing with Diaspora experiences in writing and poetry.
Lyublyanovics pays attention to political aspects of the Cuman migration e. She manages to paint a complex picture of an ambivalent and diverse diasporic group while also indicating questions which remain unanswered and which could therefore be the subject of further research. He convincingly shows how later writings and historical interpretations on both confessional sides were influenced by the conflicting experiences. In her thoughtful conclusion, Susan Einbinder pp.
The study of residences and major towns has been a focus of research for decades in Central European scholarship. However, free royal towns and residential cities represented only a very small proportion of the urban centers in medieval Central Europe. Most of the towns were limited in size and had few legal privileges compared to villages. The volume under review discusses the urban development of five or rather six towns that certainly belong to the latter category. The book consists of nine chapters, including the short but important epilogue.
They were all in royal hands in the early fourteenth century and were all given privileges together in It would have been helpful to have included the two charters on facing pages in order to allow the reader to compare the two documents more easily. The chapter draws attention to the limits of the privileges that the five towns received. The settlements hardly enjoyed any more freedoms than those usually granted to settlements of invited guests hospes. However, the towns were in a favorable position than otherwise, because with only a few short exceptions the king was their landlord until modern times.
The fourth chapter is devoted to the study of the people who settled here.
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In the Middle Ages, the region was ethnically very diverse. It was inhabited by Germans, Hungarians, Ruthenians, and Romanians. The early bestowal of privileges reflects the granting of rights to the German settlers, but later the ethnic makeup of the towns shifted and they became more predominantly Hungarian speaking. Romanians and Ruthenians, though present in the county as of the fourteenth and the fifteenth centuries respectively, were present only in small numbers in the towns.
They inhabited the surrounding villages, and mention of them in the primary sources is connected to economic exchange between the towns and the villages of the region. The fifth chapter therefore deals with salt mining in the region. Historians would have benefitted from an archontology on the administration in the region in the Middle Ages, which has yet to have been done.
However, the chapter is a very important part of the book, as it clearly demonstrates how the extraction of a mining good was crucial in the urbanization process of a particular region. He feels at home in this chapter, as in a number of his earlier works he analyzed literacy, the issue of charters, and sealing practices in market towns in medieval Hungary.
He draws attention to the differences in the legal lives of the five towns with particular regard to their designation in charters. He also discusses the magistrates of the towns and their jurisdiction. The seventh chapter addresses the economic life of the towns. Given the lack of other sources, the professional makeup of the towns, i. The only characteristically urban feature was the relatively high number of learned people literatus , but this can be easily explained by the need for literate people to manage the administration of salt mining.
The penultimate chapter is seemingly a small digression from the main focus of the book, which is the study of the five aforementioned towns. It discusses the sixth urban settlement in the county, Ruske Pole. The settlement began to develop a century later than the other towns, and it was never granted the liberties that the other towns received. However, it lies in the geographic center of the region and thus may have served as a market center for regional trade.
This is indicated by a market privilege from the early sixteenth century that provided as much as four annual fairs to the town.